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Mu-driven transposition of recombinant mini-Mu unit DNA
Mu-driven transposition of recombinant mini-Mu unit DNA within the Corynebacterium glutamicum chromosome.
A dual-component Mu-transposition system was modified for the mixing/amplification of genes in Corynebacterium. The system consists of two varieties of plasmids: (i) a non-replicative integrative plasmid that accommodates the transposing mini-Mu(LR) unit bracketed by the L/R Mu ends or the mini-Mu(LER) unit, which moreover accommodates the enhancer component, E, and (ii) an integration helper plasmid that expresses the transposition issue genes for MuA and MuB.
Environment friendly transposition within the C. glutamicum chromosome (≈ 2 × 10-Four per cell) occurred primarily by the replicative pathway by way of cointegrate formation adopted by doable decision. Optimizing the E location within the mini-Mu unit considerably elevated the effectivity of Mu-driven intramolecular transposition-amplification in C. glutamicum in addition to in gram-negative micro organism.
The brand new C. glutamicum genome modification technique that was developed permits the resultant unbiased integration/amplification/fixation of goal genes at excessive copy numbers. After integration/amplification of the primary mini-Mu(LER) unit within the C. glutamicum chromosome, the E-element, which is bracketed by lox-like websites, is excised by Cre-mediated vogue, thereby fixing the truncated mini-Mu(LR) unit in its place for the following integration/ amplification of recent mini-Mu(LER) models. This technique was demonstrated utilizing the genes for the citrine and inexperienced fluorescent proteins, yECitrine and yEGFP, respectively.

Mouse Monoclonal Anti-human FLT-1/VEGFR-1 IgG, aff pure |
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FLT12-M | Alpha Diagnostics | 100 ug | EUR 578.4 |
Mouse Monoclonal Anti-human FLT-1/VEGFR-1 IgG, aff pure |
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FLT14-M | Alpha Diagnostics | 100 ug | EUR 578.4 |
Human Genomic DNA |
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X11000 | EpiGentek |
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Human Brain Genomic DNA |
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X11001 | EpiGentek |
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VEGFR-2, human recombinant protein |
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P1080-.1 | ApexBio | 100 µg | EUR 2314.8 |
Description: Vascular endothelial growth factor receptor 2 (VEGFR-2) belongs to the family of receptor tyrosine kinases (RTKs) and is almost exclusively restricted to endothelial cells. VEGFR-2 has a lower affinity for VEGF than the Flt-1 receptor, but a higher signaling activity |
Rabbit Anti-Mouse FLT-1/VEGFR-1 (279-299aa) IgG, aff pure |
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FLT15-A | Alpha Diagnostics | 100 ul | EUR 578.4 |
Polyclonal Goat anti-GST α-form |
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GST-ANTI-1 | Detroit R&D | 50 uL | EUR 336 |
VEGFR Tyrosine Kinase Inhibitor II |
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C4603-1 | ApexBio | 1 mg | EUR 141.6 |
Histone H3 Methylation Antibody Panel Pack I – Active Genes |
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C10000 | EpiGentek |
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Histone H3 Methylation Antibody Panel Pack I – Repression Genes |
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C10001 | EpiGentek |
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Histone H3 Methylation Antibody Panel Pack II – Active Genes |
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C10002 | EpiGentek |
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Histone H3 Methylation Antibody Panel Pack II – Repression Genes |
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C10003 | EpiGentek |
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Histone H3 Methylation Antibody Panel Pack III – Active Genes |
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C10004 | EpiGentek |
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Histone H3K4 Methylation Antibody Panel Pack |
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C10005 | EpiGentek |
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Histone H3K9 Methylation Antibody Panel Pack |
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C10006 | EpiGentek |
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Histone H3K27 Methylation Antibody Panel Pack |
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C10007 | EpiGentek |
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Histone H3K36 Methylation Antibody Panel Pack |
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C10008 | EpiGentek |
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Histone H3K79 Methylation Antibody Panel Pack |
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C10009 | EpiGentek |
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Histone H3 Acetylation Antibody Panel Pack I |
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C10010 | EpiGentek |
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Histone H3 Acetylation Antibody Panel Pack II |
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C10011 | EpiGentek |
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Histone H4K20 Methylation Antibody Panel Pack |
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C10012 | EpiGentek |
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Histone H4 Acetylation Antibody Panel Pack |
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C10013 | EpiGentek |
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Histone H3 Phosphorylation Antibody Panel Pack |
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C10014 | EpiGentek |
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Histone H3R2 Methylation Antibody Panel Pack |
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C10015 | EpiGentek |
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Histone H3R8 Methylation Antibody Panel Pack |
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C10016 | EpiGentek |
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Histone H3R17 Methylation Antibody Panel Pack |
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C10017 | EpiGentek |
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Histone H3R26 Methylation Antibody Panel Pack |
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C10018 | EpiGentek |
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Histone H4R3 Methylation Antibody Panel Pack |
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C10019 | EpiGentek |
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DNMT3A Protein |
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E11000 | EpiGentek |
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TET1 Protein (Active) |
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E12002 | EpiGentek |
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DNMT3B Protein |
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E14000 | EpiGentek |
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DNMT1 Protein |
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E15000 | EpiGentek |
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HDAC1 Protein |
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E24002 | EpiGentek |
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HDAC10 Protein |
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E24003 | EpiGentek |
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HDAC11 Protein |
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E24004 | EpiGentek |
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HDAC2 Protein |
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E24005 | EpiGentek |
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HDAC3 Protein |
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E24006 | EpiGentek |
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HDAC4 Protein |
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E24007 | EpiGentek |
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HDAC5 Protein |
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E24008 | EpiGentek |
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HDAC6 Protein |
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E24009 | EpiGentek |
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HDAC7 Protein |
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E24010 | EpiGentek |
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HDAC8 Protein |
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E24011 | EpiGentek |
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HDAC9 Protein |
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E24012 | EpiGentek |
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H3F3A Protein |
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E35003 | EpiGentek |
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H4 Protein |
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E35005 | EpiGentek |
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SOD1 Protein |
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E70000 | EpiGentek |
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EpiMag HT (96-Well) Magnetic Separator |
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Q10002 | EpiGentek |
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EpiMag 96-Well Microplate (5/pack) |
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Q10003 | EpiGentek |
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DNA Methylation Antibody Panel Pack I |
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C20000 | EpiGentek |
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Rabbit Anti-Mouse FLT-4/VEGFR-3 IgG #1, aff pure |
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FLT41-A | Alpha Diagnostics | 100 ug | EUR 578.4 |
SARS-CoV-2 Spike S1 RBD Protein, Human Fc-Fusion, Avi-Tag |
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E80025 | EpiGentek |
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Mouse FLT-4/VEGFR-3 Control/blocking peptide #1 |
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FLT41-P | Alpha Diagnostics | 100 ug | EUR 196.8 |
Anti-Flt-1 antibody |
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STJ93093 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Rabbit polyclonal to Flt-1. |
Anti-Flt-1 antibody |
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STJ93094 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Rabbit polyclonal to Flt-1. |
Anti-Flt-1 antibody |
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STJ98080 | St John's Laboratory | 100 µl | EUR 280.8 |
Description: Mouse monoclonal to Flt-1. |
ACE2, His-Tag Protein |
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E80019 | EpiGentek |
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SARS-CoV-2 Spike S1 (13-665) Protein, Fc Fusion, Avi-tag |
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E80020 | EpiGentek |
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SARS-CoV-2 Spike S1 (16-685) Protein, Avi-His-tag |
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E80021 | EpiGentek |
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SARS-CoV-2 Spike S1 (16-685) Protein, Fc Fusion, Avi-tag |
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E80022 | EpiGentek |
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SARS-CoV-2 Spike S1 RBD (V367F) Protein, Avi-His-tag |
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E80023 | EpiGentek |
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SARS-CoV-2 Spike S1 RBD Protein, Avi-His-tag |
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E80024 | EpiGentek |
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SARS-CoV-2 Spike S1 RBD Protein, Mouse Fc-fusion |
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E80026 | EpiGentek |
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SARS-CoV-2 Nucleocapsid Protein, Avi-His-tag |
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E80027 | EpiGentek |
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Recombinant SARS-CoV-2 Spike Glycoprotein(S) (D614G), Partial |
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E80028 | EpiGentek |
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Anti-human PD-1, PE-labeled |
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71290-1 | BPS Bioscience | 50 µg | EUR 355 |
Description: R-Phycoerythrin-labeled anti-PD-1 neutralizing recombinant murine/human chimeric antibody recognizing the PD-L1/PD-L2 binding region of human PD-1. This antibody does not cross-react with mouse PD-1, but does cross-react with monkey (M. fascicularis) PD-1. It has not been tested with other species. |
Rabbit Anti-Human FLT-4/VEGFR-3 IgG #2, aff pure |
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FLT42-A | Alpha Diagnostics | 100 ug | EUR 578.4 |
Anti-Periphilin 1 Antibody |
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A06996-1 | BosterBio | 100ul | EUR 476.4 |
Description: Rabbit Polyclonal Antibody for Periphilin 1 Antibody (PPHLN1) detection.tested for WB in Human, Mouse. |
Anti-Lyl-1 Antibody |
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A07491-1 | BosterBio | 100ul | EUR 476.4 |
Description: Rabbit Polyclonal Lyl-1 Antibody. Validated in IHC and tested in Human, Mouse, Rat. |
Anti-GLI-1 Antibody |
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A07972-1 | BosterBio | 100ul | EUR 476.4 |
Description: Rabbit Polyclonal Antibody for GLI-1 Antibody (ACSS1) detection. Tested with WB in Human, Mouse, Rat. |
Anti-Cerebellin 1 Antibody |
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A09176-1 | BosterBio | 100ul | EUR 476.4 |
Description: Rabbit Polyclonal Antibody for Cerebellin 1 Antibody (CBLN1) detection. Tested with WB in Human, Mouse, Rat. |
Anti-DOC-1 Antibody |
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A09467-1 | BosterBio | 100ul | EUR 476.4 |
Description: Rabbit Polyclonal Antibody for DOC-1 Antibody (CDK2AP1) detection. Tested with WB in Human, Mouse. |
Anti-NPDC-1 Antibody |
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A12846-1 | BosterBio | 100ul | EUR 476.4 |
Description: Rabbit Polyclonal Antibody for NPDC-1 Antibody (NPDC1) detection. Tested with WB in Human, Mouse, Rat. |
Anti-ROBO-1 Antibody |
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A01530-1 | BosterBio | 100ug | EUR 546 |
Description: Rabbit Polyclonal ROBO-1 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat. |
Anti-Bag-1 Antibody |
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A02423-1 | BosterBio | 50 ul | EUR 476.4 |
Description: Rabbit Polyclonal Bag-1 Antibody. Validated in IP, IHC and tested in Bovine, Canine, Human, Mouse, Rat. |
Anti-TUB 1 Antibody |
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A02917-1 | BosterBio | 100ug/vial | EUR 352.8 |
Anti-Dok-1 Antibody |
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A03039-1 | BosterBio | 100ul | EUR 476.4 |
Description: Rabbit Polyclonal Antibody for Dok-1 Antibody (DOK1) detection.tested for WB in Human, Mouse, Rat. |
Anti-TFIIIB90-1 Antibody |
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A03761-1 | BosterBio | 100ul | EUR 476.4 |
Description: Rabbit Polyclonal Antibody for TFIIIB90-1 Antibody (BRF1) detection.tested for WB in Human, Mouse. |
Anti-Atrophin-1 Antibody |
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A03828-1 | BosterBio | 100ul | EUR 476.4 |
Description: Rabbit Polyclonal Antibody for Atrophin-1 Antibody (ATN1) detection. Tested with WB in Human, Mouse, Rat. |
Anti-CNG-1 Antibody |
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A05494-1 | BosterBio | 100ul | EUR 476.4 |
Description: Rabbit Polyclonal Antibody for CNG-1 Antibody (CNGA1) detection. Tested with WB in Human, Mouse, Rat. |
Anti-PAI-1 Antibody |
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A00637-1 | BosterBio | 100ul | EUR 476.4 |
Description: Rabbit Polyclonal Antibody for PAI-1 Antibody (SERPINE1) detection.tested for WB in Human, Mouse, Rat. |
Anti-Flk-1 Antibody |
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A00901-1 | BosterBio | 100ul | EUR 476.4 |
Description: Rabbit Polyclonal Antibody for Flk-1 Antibody (KDR) detection.tested for WB in Human, Mouse. |
Anti-EDG-1 Antibody |
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A01502-1 | BosterBio | 100ul | EUR 476.4 |
Description: Rabbit Polyclonal Antibody for EDG-1 Antibody (S1PR1) detection.tested for WB in Human, Mouse, Rat. |
Anti-PARP-1 Antibody |
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A00122-1 | BosterBio | 100ul | EUR 476.4 |
Description: Rabbit Polyclonal PARP-1 Antibody. Validated in ELISA, IP, IF, WB and tested in Human, Mouse. |
Anti-Presenilin 1 Antibody |
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A00138-1 | BosterBio | 100ul | EUR 476.4 |
Description: Rabbit Polyclonal Antibody for Presenilin 1 Antibody (PSEN1) detection. Tested with WB, IHC in Human, Mouse, Rat. |
Methylamp 96 DNA Modification Kit |
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P-1008 | EpiGentek |
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Nucleic Acid Isolation Enhancer (Glycogen Solution) |
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R-1001 | EpiGentek |
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Methylamp PCR Enhancer |
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R-1002 | EpiGentek |
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Streptavidin: HRP Conjugate |
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R-1098 | EpiGentek |
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Streptavidin |
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R-1100 | EpiGentek |
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Outcomes of cytomegalovirus DNA viral hundreds expressed in copies per millilitre and worldwide models per millilitre are equal.
Quantification of Cytomegalovirus (CMV) DNA is required for the initiation and monitoring of anti-viral remedy and the detection of viral resistance. Nonetheless, because of the lack of standardisation of CMV DNA nucleic acid checks, it’s troublesome to set common thresholds. In 2010, the 1st WHO Worldwide Normal for Human Cytomegalovirus for Nucleic Acid Amplification Strategies was launched. Since then CMV DNA viral load assays have been calibrated utilizing this normal.
Three exterior high quality evaluation (EQA) suppliers despatched the identical 5 samples to their contributors and analysed the outcomes to find out the equivalence of reporting CMV DNA leads to worldwide models per millilitre (IU/mL), and in contrast the distinction in outcomes reported in IU/mL with these reported in copies per millilitre (c/mL), and to find out the speed of adoption of IU/mL. About 78% of contributors proceed to report leads to c/mL although six of the 12 industrial assays are calibrated towards the usual.
The vary of the outcomes reported in IU/mL was lower than these reported in c/mL indicating that the adoption of the WHO normal efficiently improved the reporting of the CMV viral load.
The variation in particular person pattern outcomes reported by completely different assays, no matter whether or not in IU/mL or c/mL, continues to be nice and subsequently extra standardisation of the assays is required to permit the setting of remedy and monitoring thresholds. This research can act as a bench mark to find out price of future adoption if reporting CMV DNA viral load leads to IU/mL.
S1 satellite tv for pc DNA repetitive models show equivalent construction and total variability in all Anatolian brown frog taxa.
S1 satellite tv for pc DNA from Palearctic brown frogs has a species-specific construction in all European species. We characterised S1 satellite tv for pc DNA from the Anatolian brown frogs Rana macrocnemis, R. camerani, and R. holtzi as a way to outline their taxonomic rank and the construction of this satellite tv for pc on this frog lineage. Southern blots of genomic DNA digested with KpnI, EcoRV, NdeI, NheI, or StuI produced the identical sample of satellite tv for pc DNA bands. Furthermore, quantitative dot blots confirmed that this satellite tv for pc DNA accounts for 0.1 % of the genome in all taxa.
- Evaluation of the general genomic variability of the S1a repeat sequence in specimens from numerous populations demonstrated that this repetitive unit additionally has the identical dimension (476 bp), the identical most typical sequence (MCS) and the identical total variability in all three taxa, and in addition in R. macrocnemis tavasensis.
- The S1a repetitive unit presents three deletions of 9, eight and 1 bp in comparison with the 494-bp S1a repeat from European frogs. The S1a MCS has three variable positions (sequence WWTK in positions 183-186), because of the presence of two repeat subpopulations with motifs AATG and WWTT in all taxa. In contrast to beforehand analyzed mitochondrial and nuclear sequences that present appreciable variations amongst these taxa, no distinction could possibly be detected within the construction and variability of the S1 satellite tv for pc repetitive models.
- This implies that these taxa ought to belong to a single species. Our outcomes point out that this satellite tv for pc DNA selection most likely shaped when the Anatolian lineage radiated from widespread ancestor about Four mya, and since then has maintained its construction in all 4 taxa examined.
Dkk-1 Polyclonal Antibody |
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ABP53293-003ml | Abbkine | 0.03ml | EUR 189.6 |
Description: A polyclonal antibody for detection of Dkk-1 from Human, Mouse, Rat. This Dkk-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Dkk-1 |
Dkk-1 Polyclonal Antibody |
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ABP53293-01ml | Abbkine | 0.1ml | EUR 346.8 |
Description: A polyclonal antibody for detection of Dkk-1 from Human, Mouse, Rat. This Dkk-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Dkk-1 |
Dkk-1 Polyclonal Antibody |
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ABP53293-02ml | Abbkine | 0.2ml | EUR 496.8 |
Description: A polyclonal antibody for detection of Dkk-1 from Human, Mouse, Rat. This Dkk-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Dkk-1 |
Dkk-1 Polyclonal Antibody |
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ES4292-100ul | ELK Biotech | 100ul | EUR 334.8 |
Description: A Rabbit Polyclonal antibody against Dkk-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
Dkk-1 Polyclonal Antibody |
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ES4292-50ul | ELK Biotech | 50ul | EUR 248.4 |
Description: A Rabbit Polyclonal antibody against Dkk-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
DKK-1 Recombinant Protein |
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40-225-0002mg | ProSci | 0.002 mg | EUR 311.1 |
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 expressed in human 293 cells is a 35-40 kDa glycoprotein containing 235 amino-acid residues. |
DKK-1 Recombinant Protein |
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40-225-001mg | ProSci | 0.01 mg | EUR 437.1 |
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 expressed in human 293 cells is a 35-40 kDa glycoprotein containing 235 amino-acid residues. |
Dkk-1 Polyclonal Antibody |
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41928-100ul | SAB | 100ul | EUR 302.4 |
Dkk-1 Polyclonal Antibody |
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41928-50ul | SAB | 50ul | EUR 224.4 |
DKK 1 Recombinant Protein |
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96-236 | ProSci | 0.1 mg | EUR 752.1 |
Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK1 takes part in embryonic development through its inhibition of the WNT signaling pathway, binds to LRP6 with high affinity and prevents the Frizzled-Wnt-LRP6 complex formation in response to Wnts. DKK1 promotes LRP6 internalization and degradation when it forms a ternary complex with the cell surface receptor Kremen.DKK1 not olny functions as a head inducer during development, but also regulates joint remodeling and bone formation, which suggests roles for DKK1 in the pathogenesis of rheumatoid arthritis and multiple myeloma. More recently research reported, DKK1 impacts eye development from a defined developmental time point on, and is critical for lens separation from the surface ectoderm via β-catenin mediated Pdgfrα and E-cadherin expression. |
DKK 1 Recombinant Protein |
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96-237 | ProSci | 0.025 mg | EUR 619.8 |
Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK1 takes part in embryonic development through its inhibition of the WNT signaling pathway, binds to LRP6 with high affinity and prevents the Frizzled-Wnt-LRP6 complex formation in response to Wnts. DKK1 promotes LRP6 internalization and degradation when it forms a ternary complex with the cell surface receptor Kremen.DKK1 not olny functions as a head inducer during development, but also regulates joint remodeling and bone formation, which suggests roles for DKK1 in the pathogenesis of rheumatoid arthritis and multiple myeloma. More recently research reported, DKK1 impacts eye development from a defined developmental time point on, and is critical for lens separation from the surface ectoderm via β-catenin mediated Pdgfrα and E-cadherin expression. |
Dkk-1 Recombinant Protein |
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96-861 | ProSci | 0.1 mg | EUR 651.3 |
Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK1 takes part in embryonic development through its inhibition of the WNT signaling pathway, binds to LRP6 with high affinity and prevents the Frizzled-Wnt-LRP6 complex formation in response to Wnts. DKK1 promotes LRP6 internalization and degradation when it forms a ternary complex with the cell surface receptor Kremen.DKK1 not olny functions as a head inducer during development, but also regulates joint remodeling and bone formation, which suggests roles for DKK1 in the pathogenesis of rheumatoid arthritis and multiple myeloma. More recently research reported, DKK1 impacts eye development from a defined developmental time point on, and is critical for lens separation from the surface ectoderm via beta-catenin mediated Pdgfralpha and E-cadherin expression. |
Dkk-1 Recombinant Protein |
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96-990 | ProSci | 0.05 mg | EUR 714.3 |
Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK1 takes part in embryonic development through its inhibition of the WNT signaling pathway, binds to LRP6 with high affinity and prevents the Frizzled-Wnt-LRP6 complex formation in response to Wnts. DKK1 promotes LRP6 internalization and degradation when it forms a ternary complex with the cell surface receptor Kremen.DKK1 not olny functions as a head inducer during development, but also regulates joint remodeling and bone formation, which suggests roles for DKK1 in the pathogenesis of rheumatoid arthritis and multiple myeloma. More recently research reported, DKK1 impacts eye development from a defined developmental time point on, and is critical for lens separation from the surface ectoderm via beta-catenin mediated Pdgfralpha and E-cadherin expression. |
Anti-Dkk-1 antibody |
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STJ97257 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Rabbit polyclonal to Dkk-1. |
Anti-Dkk-1 antibody |
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STJ98000 | St John's Laboratory | 100 µl | EUR 280.8 |
Description: Mouse monoclonal to Dkk-1. |
Dkk-2 |
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GT15222 | Neuromics | 100 ug | EUR 631.2 |
Human DKK-1 PicoKine ELISA Kit |
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EK0867 | BosterBio | 96 wells | EUR 510 |
Description: For quantitative detection of human DKK1 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
ELISA kit for Human DKK-1 |
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EK5390 | SAB | 96 tests | EUR 663.6 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Human DKK-1 in samples from serum, plasma, tissue homogenates and other biological fluids. |
Dkk-1 Polyclonal Conjugated Antibody |
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C41928 | SAB | 100ul | EUR 476.4 |
DKK-1 (CHO-expressed), Mouse |
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HY-P7154 | MedChemExpress | 50ug | EUR 914.4 |
Recombinant Mouse Dkk-1 Protein |
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RP01062 | Abclonal | 5 μg | EUR 219.6 |
Human DKK-1 ELISA kit (4×96T) |
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LF-EK50798 | Abfrontier | 4×96T | EUR 2641.2 |
Nori® Human DKK-1 ELISA Kit |
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GR106268 | Genorise Scientific | 96-well | EUR 553.2 |
Dkk-3 antibody |
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22898-100ul | SAB | 100ul | EUR 468 |
DKK-3 ELISA KIT|Human |
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EF000091 | Lifescience Market | 96 Tests | EUR 826.8 |
Recombinant Human Dkk-3 Protein |
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RP00355 | Abclonal | 10 μg | EUR 196.8 |
ELISA kit for Rat DKK-1 |
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EK5668 | SAB | 96 tests | EUR 663.6 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Rat DKK-1 in samples from serum, plasma, tissue homogenates and other biological fluids. |
Human DKK-1(Dickkopf-related protein 1) ELISA Kit |
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EH0113 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
Dkk-1 ELISA Kit (Human) : 96 Wells (OKAG00221) |
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OKAG00221 | Aviva Systems Biology | 96 Wells | EUR 715.2 |
Description: Description of target: This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.;Species reactivity: Human;Application: ELISA;Assay info: Quantitative Colorimentric Sandwich ELISA;Sensitivity: 63 pg/mL |
Dkk-3 Polyclonal Antibody |
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ABP54542-003ml | Abbkine | 0.03ml | EUR 189.6 |
Description: A polyclonal antibody for detection of Dkk-3 from Human, Mouse. This Dkk-3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160 |
Dkk-3 Polyclonal Antibody |
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ABP54542-01ml | Abbkine | 0.1ml | EUR 346.8 |
Description: A polyclonal antibody for detection of Dkk-3 from Human, Mouse. This Dkk-3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160 |
Dkk-3 Polyclonal Antibody |
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ABP54542-02ml | Abbkine | 0.2ml | EUR 496.8 |
Description: A polyclonal antibody for detection of Dkk-3 from Human, Mouse. This Dkk-3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160 |
Dkk-3 Polyclonal Antibody |
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ES5541-100ul | ELK Biotech | 100ul | EUR 334.8 |
Description: A Rabbit Polyclonal antibody against Dkk-3 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA |
Dkk-3 Polyclonal Antibody |
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ES5541-50ul | ELK Biotech | 50ul | EUR 248.4 |
Description: A Rabbit Polyclonal antibody against Dkk-3 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA |
DKK-2 Recombinant Protein |
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40-651 | ProSci | 2 ug | EUR 311.1 |
Description: The dickkopf (DKK)-related protein family is comprised of four central members, DKK-1 - 4, along with the distantly-related DKK family member DKK-11 (Soggy), which is thought to be a descendent of an ancestral DKK-3 precursor due to its unique sequence homology to DKK-3 and no other DKK family member. DKK family members, with the exception of the divergent Soggy, share two conserved cysteine-rich domains and show very little sequence similarity outside of these domains. Playing an important regulatory role in vertebrate development through localized inhibition of Wnt-regulated processes, including anterior-posterior axial patterning, limb development, somitogenesis, and eye formation, DKKs have also been implicated post-developmentally in bone formation, bone disease, cancer, and neurodegenerative diseases. DKK proteins typically play an important regulatory role in the Wnt/β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/β-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/β-catenin signaling cascade. DKK-2 has been shown to both inhibit and enhance canonical Wnt signaling; enhancing Wnt signaling through direct high-affinity binding of DKK-2 to LRP6 during LRP6 overexpression, while inhibiting Wnt signaling and promoting LRP6 internalization through the formation of a ternary complex between DKK-2, LRP6, and Kremen-2. Recombinant Human DKK-2 expressed in CHO cells is a glycoprotein that has a calculated molecular weight of 25.8 kDa and contains 234 amino acid residues. Due to glycosylation, human DKK-2 migrates at an apparent molecular weight of approximately 31-36 kDa by SDS-PAGE analysis under non-reducing conditions. |
DKK-3 Recombinant Protein |
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40-652 | ProSci | 2 ug | EUR 311.1 |
Description: The dickkopf (DKK)-related protein family is comprised of four central members, DKK-1 - 4, along with the distantly-related DKK family member DKK-L1 (Soggy), which is thought to be a descendent of an ancestral DKK-3 precursor due to its unique sequence homology to DKK-3 and no other DKK family member. DKK family members, with the exception of the divergent Soggy, share two conserved cysteine-rich domains and show very little sequence similarity outside of these domains. Playing an important regulatory role in vertebrate development through localized inhibition of Wnt-regulated processes, including anterior-posterior axial patterning, limb development, somitogenesis, and eye formation, DKKs have also been implicated post-developmentally in bone formation, bone disease, cancer, and neurodegenerative diseases. DKK proteins typically play an important regulatory role in the Wnt/β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/β-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/β-catenin signaling cascade. DKK-3 has been shown to potentiate, rather than inhibit, Wnt signaling through interactions with the high-affinity, transmembrane co-receptors Kremen-1 (Krm1) and Kremen-2 (Krm2). Recombinant Human DKK-3 expressed in CHO cells is a glycoprotein that has a calculated molecular weight of 36.3 kDa and contains 329 amino acid residues. Due to glycosylation, Human DKK-3 migrates at an apparent molecular weight of approximately 39-49 kDa by SDS-PAGE analysis under non-reducing conditions. |
DKK 3 Recombinant Protein |
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96-239 | ProSci | 0.2 mg | EUR 821.4 |
Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK3 has been proposed as tumour suppressor gene and a marker for tumour blood vessels. DKK3 is the only DKK family member abundantly expressed in normal lung, but silenced by promoter hypermethylation in a large fraction of lung cancer cell lines and lung tumors. Downregulation of DKK3 was correlated with tumor progression and expression of nuclear beta-catenin in lung tumors. Ectopic expression of DKK3 in lung cancer cells with DKK3 hypermethylation induced apoptosis and inhibited TCF-4 activity as well as nuclear accumulation of beta-catenin and expression of TCF-4 targets c-Myc and cyclin D1. DKK3 modulates FGF and Activin/Nodal signaling to regulate mesoderm induction during early Xenopus development, was reported. |
Dkk-3 Recombinant Protein |
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96-991 | ProSci | 0.05 mg | EUR 651.3 |
Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK3 has been proposed as tumour suppressor gene and a marker for tumour blood vessels. DKK3 is the only DKK family member abundantly expressed in normal lung, but silenced by promoter hypermethylation in a large fraction of lung cancer cell lines and lung tumors. Downregulation of DKK3 was correlated with tumor progression and expression of nuclear beta-catenin in lung tumors. Ectopic expression of DKK3 in lung cancer cells with DKK3 hypermethylation induced apoptosis and inhibited TCF-4 activity as well as nuclear accumulation of beta-catenin and expression of TCF-4 targets c-Myc and cyclin D1. DKK3 modulates FGF and Activin/Nodal signaling to regulate mesoderm induction during early Xenopus development, was reported. |
Anti-Dkk-3 antibody |
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STJ92720 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Rabbit polyclonal to Dkk-3. |
Anti-Dkk-3 antibody |
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STJ98001 | St John's Laboratory | 100 µl | EUR 280.8 |
Description: Mouse monoclonal to Dkk-3. |
Human DKK-4 PicoKine ELISA Kit |
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EK0868 | BosterBio | 96 wells | EUR 546 |
Description: For Quantitative Detection of human DKK-4 in cell culture supernates, serum and plasma(heparin, EDTA). |
Human DKK-3 PicoKine ELISA Kit |
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EK1323 | BosterBio | 96 wells | EUR 510 |
Description: For quantitative detection of human DKK-3 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
DKK-3 ELISA Kit (Human) (OKBB00603) |
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OKBB00603 | Aviva Systems Biology | 96 Wells | EUR 606 |
Description: Description of target: Dickkopf-related protein 3 is a protein that in humans is encoded by the DKK3 gene. This gene encodes a protein that is a member of the dickkopf family. It is mapped to 11p15.3. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Members of the Dkk-related family display unique patterns of mRNA expression in human and mouse tissues, and are secreted when expressed in 293T cells. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: <= 10 pg/mL |
Recombinant Human Dkk-3/DKK3 Protein |
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RP00209 | Abclonal | 10 μg | EUR 186 |
Nori® Mouse DKK-1 ELISA Kit |
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GR117408 | Genorise Scientific | 96-well | EUR 461 |
Nori® Mouse DKK-1 ELISA Kit |
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GR117418 | Genorise Scientific | 96-well | EUR 461 |
Nori® Human DKK-1 ELISA Kit (2 plates) |
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GR106268-2 | Genorise Scientific | 2 x 96-well | EUR 998.4 |
Human Genomic DNA |
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X11000 | EpiGentek |
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Human Brain Genomic DNA |
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X11001 | EpiGentek |
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Recombinant Dkk-1 Protein (Thr 32-His 266) [Fc] |
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VAng-1451Lsx-100g | Creative Biolabs | 100 µg | EUR 1017.6 |
Description: Human Dkk-1, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1) |
Recombinant Dkk-1 Protein (Thr 32-His 266) [Fc] |
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VAng-1451Lsx-1mg | Creative Biolabs | 1 mg | EUR 5668.8 |
Description: Human Dkk-1, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1) |
Recombinant Dkk-1 Protein (Thr 32-His 266) [His] |
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VAng-1453Lsx-100g | Creative Biolabs | 100 µg | EUR 1215.6 |
Description: Human Dkk-1, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1) |
Recombinant Dkk-1 Protein (Thr 32-His 266) [His] |
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VAng-1453Lsx-1mg | Creative Biolabs | 1 mg | EUR 5998.8 |
Description: Human Dkk-1, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1) |
Recombinant Dkk-1 Protein (Thr 32-His 266) [Strep] |
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VAng-1454Lsx-1mg | Creative Biolabs | 1 mg | EUR 7648.8 |
Description: Human Dkk-1, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1) |
Recombinant Dkk-1 Protein (Thr 32-His 266) [Strep] |
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VAng-1454Lsx-250g | Creative Biolabs | 250 µg | EUR 2964 |
Description: Human Dkk-1, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1) |
Recombinant Dkk-1 Protein (Thr 32-His 266) [Strep] |
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VAng-1454Lsx-25g | Creative Biolabs | 25 µg | EUR 918 |
Description: Human Dkk-1, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1) |
Recombinant Dkk-1 Protein (Thr 32-His 272) [His] |
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VAng-1455Lsx-500g | Creative Biolabs | 500 µg | EUR 5338.8 |
Description: Mouse Dkk-1, His tag, is expressed in HEK 293 cells. (Uniprot ID: O54908) |
Recombinant Dkk-1 Protein (Thr 32-His 272) [His] |
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VAng-1455Lsx-50g | Creative Biolabs | 50 µg | EUR 1215.6 |
Description: Mouse Dkk-1, His tag, is expressed in HEK 293 cells. (Uniprot ID: O54908) |
SARS-CoV-2 Spike S1 RBD Protein, Human Fc-Fusion, Avi-Tag |
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E80025 | EpiGentek |
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Human DKK-3(Dickkopf-related protein 3) ELISA Kit |
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EH0114 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 37.5pg/ml |
Recombinant Dkk-1 Protein (Thr 32-His 266) [Fc] [Avi] |
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VAng-1452Lsx-200g | Creative Biolabs | 200 µg | EUR 4612.8 |
Description: Biotinylated Human Dkk-1, Fc tag and Avi tag, is expressed in HEK 293 cells. (Uniprot ID: O94907-1) |
Recombinant Dkk-1 Protein (Thr 32-His 266) [Fc] [Avi] |
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VAng-1452Lsx-25g | Creative Biolabs | 25 µg | EUR 1215.6 |
Description: Biotinylated Human Dkk-1, Fc tag and Avi tag, is expressed in HEK 293 cells. (Uniprot ID: O94907-1) |
Histone H3 Methylation Antibody Panel Pack I – Active Genes |
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C10000 | EpiGentek |
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Histone H3 Methylation Antibody Panel Pack I – Repression Genes |
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C10001 | EpiGentek |
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Histone H3 Methylation Antibody Panel Pack II – Active Genes |
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C10002 | EpiGentek |
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Histone H3 Methylation Antibody Panel Pack II – Repression Genes |
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C10003 | EpiGentek |
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Histone H3 Methylation Antibody Panel Pack III – Active Genes |
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C10004 | EpiGentek |
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Histone H3K4 Methylation Antibody Panel Pack |
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C10005 | EpiGentek |
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Histone H3K9 Methylation Antibody Panel Pack |
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C10006 | EpiGentek |
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Histone H3K27 Methylation Antibody Panel Pack |
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C10007 | EpiGentek |
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Histone H3K36 Methylation Antibody Panel Pack |
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C10008 | EpiGentek |
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Histone H3K79 Methylation Antibody Panel Pack |
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C10009 | EpiGentek |
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Histone H3 Acetylation Antibody Panel Pack I |
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C10010 | EpiGentek |
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Histone H3 Acetylation Antibody Panel Pack II |
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C10011 | EpiGentek |
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Histone H4K20 Methylation Antibody Panel Pack |
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C10012 | EpiGentek |
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Histone H4 Acetylation Antibody Panel Pack |
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C10013 | EpiGentek |
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Histone H3 Phosphorylation Antibody Panel Pack |
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C10014 | EpiGentek |
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Histone H3R2 Methylation Antibody Panel Pack |
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C10015 | EpiGentek |
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Histone H3R8 Methylation Antibody Panel Pack |
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C10016 | EpiGentek |
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Histone H3R17 Methylation Antibody Panel Pack |
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C10017 | EpiGentek |
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Histone H3R26 Methylation Antibody Panel Pack |
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C10018 | EpiGentek |
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Histone H4R3 Methylation Antibody Panel Pack |
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C10019 | EpiGentek |
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DNMT3A Protein |
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E11000 | EpiGentek |
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TET1 Protein (Active) |
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E12002 | EpiGentek |
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DNMT3B Protein |
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E14000 | EpiGentek |
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DNMT1 Protein |
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E15000 | EpiGentek |
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HDAC1 Protein |
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E24002 | EpiGentek |
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HDAC10 Protein |
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E24003 | EpiGentek |
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